Blepharitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Volunteer to participate in this clinical study and sign the informed consent form; 2. No gender limit, age 18-70 years; 3. Patients clinically diagnosed as blepharitis have not received local or systemic anti-mite treatment in the past 14 days; 4. Other options of the study eye: the right eye of the patient; 5. Have not participated in other drug clinical trials within 2 weeks of the trial; 6. He is not using other drugs to treat dry eyes, or is using other drugs to treat dry eyes but has stopped taking drugs for more than 2 weeks.
Exclusion criteria
Exclusion criteria: 1. Clinically, it is supposed to be a patient with fungal, bacterial or viral keratoconjunctivitis in active stage; 2. Those with other obvious conjunctival, corneal and iris lesions; 3. Tear film rupture time=0 seconds, or tear secretion test=0 mm/5 minutes; 4. The number of staining points of the whole cornea is more than 30, and there is flaky color fusion or filamentous matter; 5. Complicated with severe primary diseases such as heart, cerebrovascular, liver, kidney and hematopoietic system; 6. Those who have internal eye surgery or eye injury in the past six months; 7. The patient received embolization of lacrimal dots in the last month; 8. Patients with a history of HSK infection; 9. Treatment that may affect the results (such as systemic steroid hormone and immunosuppressive treatment); 10. Long-term systemic or ocular administration may affect the study and evaluation of patients; 11. Sjogren's syndrome, systemic diseases and other eye diseases affecting the efficacy evaluation; 12. The researcher believes that there are any reasons for not participating in the test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| symptoms grading;lid margin signs;conjunctival signs;corneal signs; | — |
Countries
China
Contacts
Beijing Tongren Hospital, Capital Medical University