limited stage small-cell lung cancer
Conditions
Interventions
Test group:51Gy/30F/bid
Control Group:45Gy/30F/bid
Sponsors
Gansu Provincial Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Small cell lung cancer confirmed by histology or cytology; According to the stage of American veterans, it is limited stage small cell lung cancer; 2. Age: 18-85 years; 3. ECOG score: 0 – 2 points; 4. The function of main organs can ensure the smooth completion of treatment, that is, meet the following standards: Hemoglobin (Hb) = 90g/L; Absolute neutrophil count (ANC) = 1.5 × 109/L Platelet (PLT) = 100 × 109/L White blood cell (WBC) = 3.0 × 109/L Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) = 3 × ULN Total serum bilirubin (TBIL) = 1.5 × ULN Serum creatinine (Cr) = 1.5 × ULN or creatinine clearance = 5; ml/min 5. Lung function can tolerate radiotherapy; 6. No other malignant tumors except small cell lung cancer were confirmed; 7. Volunteer to join the study, sign the informed consent form, and have good compliance.
Exclusion criteria
Exclusion criteria: 1.Previous radiotherapy to the thorax; 2.Pregnancy or lactating women; 3.No serious concomitant systemic disorders (for example active infection, unstable cardiovascular disease) that in the opinion of the investigator would compromise the patients ability to complete the study or interfere with the evaluation of the efficacy and safety of the study treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 2 year OS; | — |
Secondary
| Measure | Time frame |
|---|---|
| PFS;Median overall survival;Local control rate;Adverse reactions; | — |
Countries
China
Contacts
Public ContactShao Lihua
Gansu Provincial Cancer Hospital
Outcome results
None listed