None listed
Conditions
Interventions
Group C:Use cyclopofol sedation
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years, regardless of gender; 2. American Anesthesiologist Classification (ASA) Grade I-II; 3. Body mass index (BMI) >=18 and <= 30kg/m2; 4. Able to understand the research process and methods, and willing to participate in the research.
Exclusion criteria
Exclusion criteria: 1. Those who have contraindications to general anesthesia or have a history of anesthesia accidents in the past; 2. Known or suspected allergy or contraindication to propofol injection, cyclopofol injection excipients, benzodiazepines, opioids, muscle relaxants, etc.; 3. Patients with brain loss, intracranial hypertension, stroke, unstable angina pectoris and myocardial infarction; 4. Respiratory insufficiency, obstructive pulmonary disease, difficult airway, or determination of difficulty in endotracheal intubation (Modified Martensite score: Grade III or Grade IV); 5. Uncontrolled diabetes or hypertension; 6. Severe liver dysfunction or severe renal insufficiency; 7. History of alcoholism or drug dependence; 8. Abuse or long-term use of narcotic, sedative and analgesic drugs; 9. Those with a history of mental illness; 10. Participants in any drug clinical trials within 1 month prior to screening; 11. Pregnant and lactating women; Fertile women or men were unwilling to use contraception throughout the trial; Subjects (including male subjects) who have a pregnancy plan within 1 month after the trial; 12. Subjects who have any other factors that the Investigator considers inappropriate for participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Loss of consciousness time;Wake up of time;Use of narcotic drugs;MOAA/S; | — |
Countries
China
Contacts
Public ContactZhentao Sun
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed