Chronic obstructive pulmonary disease, asthma
Conditions
Interventions
Case group:None
Control group:None
Sponsors
The First Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Normal group: no recent respiratory symptoms such as cough, sputum production and shortness of breath, no history of chronic respiratory diseases, and no abnormal pulmonary function test. 2. Asthma group: Patients met the diagnostic criteria of bronchial asthma in the Guidelines for the Prevention and Treatment of bronchial Asthma (2020 edition) and the Guidelines for the Global Initiative for the Prevention and Treatment of Asthma (2021) formulated by the Chinese Society of Respiratory Medicine, and patients in the chronic duration or clinical control period could be included with or without inhalation medication. 3. COPD group: Patients met the criteria for COPD assessment in the Guidelines for the Diagnosis and Treatment of chronic obstructive Pulmonary Disease (revised 2021) and the 2017 Global Strategy Report on the Diagnosis, Management and Prevention of Chronic obstructive Pulmonary Disease (GOLD Executive Summary) formulated by the Chinese Society of Respiratory Medicine, and inhaled drug therapy was included.
Exclusion criteria
Exclusion criteria: 1. Experimental group: (1) Failing to adopt the recommended inhalation device; (2) Patients with acute exacerbation of COPD and asthma patients with exacerbation (acute exacerbation of asthma refers to the sudden onset of wheezing, shortness of breath, cough, chest tightness and other symptoms, or exacerbation of the original symptoms, and is characterized by decreased expiratory flow, often induced by exposure to allergens, irritants or respiratory tract infection); (3) Other contraindications of pulmonary function tests; (4) Acute respiratory tract infection within four weeks. 2. Control group: (1) Patients with acute exacerbation of COPD and asthma patients with exacerbation (acute exacerbation of asthma refers to the sudden onset of wheezing, shortness of breath, cough, chest tightness and other symptoms, or exacerbation of the original symptoms, and is characterized by decreased expiratory flow, often induced by exposure to allergens, irritants or respiratory tract infection); (2) Other contraindications of pulmonary function tests; (3) Acute respiratory tract infection within four weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effective suction volume;Effective inspiratory time;Breath hold time after inhalation;Expiratory volume in first second;Exhaled nitric oxide test;ACT score;CAT score;mMRC score;Expiratory volume in the first second as a percentage of the estimated value; | — |
Secondary
| Measure | Time frame |
|---|---|
| Maximum suction flow; | — |
Countries
China
Contacts
Public ContactGao Yi
The First Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed