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Effect of perioperative continuous infusion of S-ketamine on the quality of postoperative recovery of patients undergoing radical mastectomy

Effect of perioperative continuous infusion of S-ketamine on the quality of postoperative recovery of patients undergoing radical mastectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200056576
Enrollment
Unknown
Registered
2022-02-08
Start date
2022-02-08
Completion date
Unknown
Last updated
2024-10-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

remifentanil group:Intraoperative continuous infusion of remifentanil 0.2-1ug/kg/min
esketamine group:Intraoperative continuous infusion of esketamine0.5-1mg/kg/h

Sponsors

Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Female patients undergoing elective radical mastectomy under general anesthesia; 2. Informed consent and voluntary participation in this experiment; 3. ASA Grade I-II; 4. BMI: 20-30 kg/m^2; 5. Aged >18 years and <60 years, can communicate normally.

Exclusion criteria

Exclusion criteria: 1. Patients with central nervous system or mental diseases; 2. Patients who are allergic to relevant anesthetic drugs; 3. Had breast surgery in the past; 4. Patients with severe heart, liver and renal insufficiency; 5. Taking psychotropic drugs before operation.

Design outcomes

Primary

MeasureTime frame
quality of recovery-40;—

Countries

China

Contacts

Public ContactGao Fang

Affiliated Hospital of Xuzhou Medical University

695055042@qq.com+86 13359689942

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026