depressive episode
Conditions
Interventions
bipolar depression test grop:Eco Light (5000 lux)
bipolar depression control group:Eco light(100lux)
unipolar depression test grop:Eco Light (5000 lux)
unipolar depression control grop:Eco light(100lux)
Sponsors
Beijing Anding Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for depression, Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), with first episode or recurrence, without psychotic symptoms; or meet DSM-5 diagnostic criteria for bipolar disorder, depressive episode, and not accompanied by psychotic symptoms; 2. Aged 18-65 years, no gender limit; 3. The 17-item Hamilton Depression Scale (HAMD-17) score during screening and baseline period: 14-24; 4. Currently taking antidepressants or mood stabilizers, the medication regimen was not changed one week before enrollment, and the medication regimen and dosage remained unchanged during treatment; 5. Subjects can understand and comply with the study requirements, and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Subjects currently or previously diagnosed with a disorder other than depressive disorder according to the MINI diagnostic criteria; 2. Subjects currently receiving MECT or other physical therapy; 3. At present, the subject has serious suicide risk, and HAMD-17 suicide risk item >=3 points; 4. Subjects with unstable physical diseases requiring medical or surgical treatment; 5. Existing or existing eye diseases, such as cataract, macular degeneration, glaucoma, retinitis pigmentosa, etc.; 6. Previous or current diagnosis of epilepsy; 7. History of drug dependence (including alcohol) within 12 months before inclusion, history of drug abuse within 1 month, or positive urine test for illicit drugs during screening; 8. Pregnant or lactating subjects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAMD total score subtracted;Difference in efficiency; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in the Epworth total score on the scale;Changes in blood indexes;Changes in fatigue scale-14;The MEQ assesses changes in circadian patterns; | — |
Countries
China
Contacts
Public ContactZhao Qian
Beijing Anding Hospital Affiliated to Capital Medical University
Outcome results
None listed