Sudden sensorineural hearing loss
Conditions
Interventions
Experimental group:Intratympanic injection of dexamethasone palmitate
Control group:Intratympanic injection of dexamethasone sodium phosphate
Sponsors
Eye, Ear, Nose and Throat Hospital of Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years; 2. Patients with unilateral hearing loss who meet the diagnostic criteria for sudden deafness; 3. The onset time of sudden deafness is within 3 weeks, and special treatment (hormone, thrombolytic and microcirculation improving drugs, etc.) has not been taken; 4. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with total deafness, conductive deafness and mixed deafness; 2. Patients with other ear diseases; 3. Patients with severe cardiac insufficiency or renal failure or respiratory failure; 4. Patients with stage II hypertension or above (systolic blood pressure >160mmHg, diastolic blood pressure >100mmHg); 5. Glaucoma; 6. Patients who have not recovered from visceral surgery or have sequelae after visceral surgery; 7. Gastric and duodenal ulcers; 8. Abnormal electrolyte metabolism; 9. Patients with diabetes or other endocrine system diseases; 10. Patients with severe hematological diseases or tumors (especially acoustic neuroma patients); 11. Patients who are allergic to the prescribed medication; 12. Mental disorders and other patients who cannot cooperate with medication and examination; 13. Patients who are nursing, pregnant or likely to become pregnant; 14. Have participated in any clinical drug trials in the past three months; 15. The investigator deemed it inappropriate for this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hearing level; | — |
Countries
China
Contacts
Public ContactRen Dongdong
Eye, Ear, Nose and Throat Hospital of Fudan University
Outcome results
None listed