A prospective study to evaluate the effectiveness of multiparameter MRI in the diagnosis of liver fibrosis after liver transplantation: comparison of liver biopsy or ultrasonic transient elastography

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200056522

Enrollment

Unknown

Registered

2022-02-07

Start date

2022-02-14

Completion date

Unknown

Last updated

2024-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver fibrosis after liver transplantation

Interventions

Gold Standard:Liver biopsy or ultrasonic transient elastography

Index test:mpMRI

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-85 years; 2. Patients after liver transplantation; 3. Patients who plan to perform liver biopsy or ultrasonic transient elastography; 4. The patient voluntarily joined the study and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with tumor; 2. Patients allergic to gadolinium contrast agent; 3. Patients with magnetic resonance contraindication; 4. Patients with serious heart and lung diseases; 5. Patients who, according to the judgment of the investigator, are not suitable to participate in this study.

Design outcomes

Primary

Measure	Time frame
T1 relaxation time;Liver hardness measurement value;Fast dispersion coefficient;Slow dispersion coefficient;Perfusion fraction;Average diffusion coefficient;Average diffusion kurtosis;Apparent diffusion coefficient;Fractional anisotropy;	—

Countries

China

Contacts

Public ContactYang Guangjie

Affiliated Hospital of Qingdao University

ygj_2815@qq.com+86 17853297979

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026