Mild cognitive impairment (MCI) or early dementia (CDR<=1 point)
Conditions
Interventions
Experimental group:Mahjong activity + drug therapy + music rhythm therapy
Control group:Drug therapy + music rhythm therapy
Sponsors
Changhe Tiancheng Rehabilitation Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Aged 50-85 years; 2. Progressive decline in cognitive function, in line with the diagnosis of DSM-V dementia (Dementia) or mild cognitive impairment (MCI); 3. CDR <= 1 point; 4. Have a certain ability to understand and express, and be able to obey most activity instructions; 5. No obvious physical impairment; 6. Accompanying family members or caregivers to participate in research activities; 7. Willingness to participate in research.
Exclusion criteria
Exclusion criteria: 1. Patients with rapidly progressive cognitive impairment whose disease course is less than half a year; 2. Patients with mental illness, such as severe depression, schizophrenia, etc.; 3. Severe hypertension, diabetes, unstable angina or uncontrolled hypertension and diabetes; 4. Severe visual impairment; 5. Serious acts of violence; 6. Unable to maintain sitting balance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes from baseline in MMSE and MoCA scale scores after 12 weeks of treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of patients with CDR <= 1;Changes from baseline in MemTrax and DSM-V cognitive domain involvement severity assessment after 12 weeks of treatment;Changes from baseline in ADSC-ADL after 12 weeks of treatment;Changes from baseline in NPI, HAMD, HAMA, and Apathy Rating Scale after 12 weeks of treatment;Change from baseline in caregiver burden after 12 weeks of treatment;Comparing different drugs combined with the same rehabilitation method, the difference in the efficacy of MCI and early dementia at 3 months; | — |
Countries
China
Contacts
Public ContactHuang Weiping
Changhe Tiancheng Rehabilitation Hospital
Outcome results
None listed