Skip to content

Efficacy and necessity of using proton pump inhibitor to prevent stress ulcer in patients with lung cancer resection

Efficacy and necessity of using proton pump inhibitor to prevent stress ulcer in patients with lung cancer resection

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200056511
Enrollment
Unknown
Registered
2022-02-07
Start date
2022-02-07
Completion date
Unknown
Last updated
2024-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

Control group:No PPI injection for prophylaxis
Drug intervention group:Prophylaxis with PPI injections

Sponsors

First Affiliated Hospital of Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Patients aged >= 18 years in good health who are in the same surgical ward and are scheduled to undergo pulmonary surgery.

Exclusion criteria

Exclusion criteria: 1. Aged > 85 years; 2. Currently there are digestive tract diseases such as peptic ulcer, gastroesophageal reflux disease, Helicobacter pylori infection, Zollinger-Ellison syndrome, upper gastrointestinal bleeding, functional dyspepsia; 3. Taking PPI within two weeks before surgery for the treatment of peptic ulcer, gastroesophageal reflux disease, Helicobacter pylori infection, Zollinger-Ellison syndrome, upper gastrointestinal bleeding, functional dyspepsia; 4. Emergency surgery.

Design outcomes

Primary

MeasureTime frame
Incidence of postoperative SU in patients;

Secondary

MeasureTime frame
Reasonable rate of preventive use of PPI injection;

Countries

China

Contacts

Public ContactHong Yun

First Affiliated Hospital of Zhejiang University School of Medicine

hong_wr@163.com+86 571 87233411

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026