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Ultrasound-guided quadratus lumborum block versus ultrasound-guided erector spinae block for perioperative analgesia in laparoscopic colorectal cancer resection: a prospective randomized controlled study

Ultrasound-guided quadratus lumborum block versus ultrasound-guided erector spinae block for perioperative analgesia in laparoscopic colorectal cancer resection: a prospective randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200056508
Enrollment
Unknown
Registered
2022-02-07
Start date
2022-01-31
Completion date
Unknown
Last updated
2024-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal tumor

Interventions

Ultrasound-guided quadratus lumborum block group (QLB group):Before general anesthesia, bilateral ultrasound-guided quadratus lumborum block was performed, and 25ml of 0.375% ropivacaine was used on e
Ultrasound-guided erector spinae block group (ESPB group):Before general anesthesia, bilateral ultrasound-guided erector spinae block was performed, using 25ml of 0.375% ropivacaine on each side, for

Sponsors

Chinese Academy of Medical Sciences Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Aged 20-65 years, American Society of Anesthesiologists Class I-III, BMI 18-25 kg/m^2.

Exclusion criteria

Exclusion criteria: 1. Preoperative fever: the axillary body temperature on the day before the operation > 37.5 ?; 2. Nerve block operation site infection; 3. Pregnant patients; 4. Those with preoperative pulmonary infection, bronchial asthma or airway hyperresponsiveness; 5. History of previous abdominal surgery; 6. Those who have heart disease and whose cardiac function is above grade II; 7. Serious heart disease before surgery, such as severe congenital heart disease, valvular disease, coronary heart disease, arrhythmia; 8. Central nervous system disease, history of stroke; 9. Combined with hepatic insufficiency and renal insufficiency; 10. History of preoperative radiotherapy and chemotherapy; 11. Long-term chronic pain history before surgery; 12. Those who have taken painkillers within 3 months before surgery.

Design outcomes

Primary

MeasureTime frame
The dose of opioid analgesics consumed by the patient;

Secondary

MeasureTime frame
Postoperative acute pain score;Measurement of coverage and scoring of nerve block analgesia;The time of first use of analgesics in the two groups after surgery;Postoperative doses of non-opioid analgesics in the two groups;Number of times sleep was interrupted by pain on the night of surgery;Incidence of postoperative analgesia-related adverse reactions, including postoperative respiratory depression, hypotension, nausea, vomiting, pruritus, etc.;Lower extremity motor hypokinesia after block assessment in PACU;The time of first getting out of bed and walking independently for more than 10 steps in the two groups after operation;

Countries

China

Contacts

Public ContactWang Qiang

Chinese Academy of Medical Sciences Cancer Hospital

wqzjbd001@163.com+86 15910636157

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026