Adult-onset immunodeficiency
Conditions
Interventions
Adult-onset immunodeficiency group:None
Sponsors
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients with opportunistic infection caused by atypical pathogens such as disseminated NTM, Burkholderia, Talaromyces marneffei, Cryptococcus neoformans, Histoplasma capsulatum, and herpes zoster virus. And the suspected diagnosis is adult-onset immunodeficiency; 2. Patients and family members understand the study and volunteer to participate in the trial, and signed an informed consent form by the person or legal guardian; 3. Aged 18 years and over.
Exclusion criteria
Exclusion criteria: 1. The patient's immunodeficiency can be explained by other causes, including congenital immunodeficiency, HIV infection, diabetes with long-term substandard blood sugar, and taking immunosuppressive drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum anti-interferon-? autoantibodies;Infection-related indicators;Immune-related indicators;Treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Nutritional status;Quality of life; | — |
Countries
China
Contacts
Public ContactWang Jinglan
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Outcome results
None listed