Breast cancer
Conditions
Interventions
case series:None
Sponsors
Women and Children's Hospital, School of Medicine, Xiamen university
Eligibility
Sex/Gender
All
Age
12 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. At least 18 years of age with breast tumor confirmed by histological examination and receiving chemotherapy regimen containing docetaxel; 2. ECOG score 0-2; 3. PS score = 12 weeks; 5. Bone marrow function: White blood cell count >= 3.0 x 10^9/L, neutrophil count >= 1.5 x 10^9/L, platelet count >= 75 x 10^9/L, hemoglobin >= 100g /L; 6. Liver and kidney function: total bilirubin <= 1.5 times upper limit, AST and ALT <= 3 times upper limit, creatinine <= 1.5 times upper limit; 7. At least 2 reliable plasma concentrations of docetaxel; 8. The patient's clinical data, such as demographics, blood routine and blood biochemistry, were complete.
Exclusion criteria
Exclusion criteria: 1. Received radiotherapy or other chemotherapy within the past 3 months; 2. Abnormal liver, kidney, heart function and blood routine; 3. Patients receiving other chemotherapy regimens during treatment; 4. Other malignant tumors; 5. Pregnant or lactation or mental disorders requiring intervention; 6. Uncontrollable infections, high blood pressure, diabetes; 7. Lack of important information, such as dose information, sampling time, etc.; 8. Patients who cannot tolerate chemotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| neutrophil count; | — |
Secondary
| Measure | Time frame |
|---|---|
| white blood cell count;Hemoglobin count;blood platelet count; | — |
Countries
China
Contacts
Public ContactChen Quanyao
Women and Children's Hospital, School of Medicine, Xiamen University
Outcome results
None listed