depression
Conditions
Interventions
Case series:None
Sponsors
the First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for unipolar depressive episodes in the tenth edition of the International Classification of Diseases (ICD-10) (HAMD-24= >= 8 points, BDI-13 >= 5 points); 2. Aged 18 to 55 years old; 3. Junior high school and above education; 4. Be able to cooperate with the physical examination before joining the group, understand and cooperate with filling in the questionnaire, Wisconsin card sorting test, etc.; 5. Voluntarily participate in the project and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with organic brain diseases, patients with serious physical diseases, such as hypertension, heart disease, diabetes, endocrine diseases, etc.; 2. Those with obvious aphasia; 3. Those who have recently suffered from persistent cold and fever or chronic inflammation; 4. Other severe mental illnesses, including (bipolar disorder, post-traumatic stress disorder, post-schizophrenia depression), etc.; 5. Patients receiving anti-inflammatory or hormonal drug therapy; 6. Severe hearing loss and visually impaired (including color discrimination); 7. Pregnant women and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Scale;Childhood Trauma Questionnaire;Baker Depression Scale;Baker Anxiety Scale;Wisconsin Card Sorting Test;IL-1ß;IL-6;IL-8;IL-10;TNF-a; | — |
Countries
China
Contacts
Public ContactHu Hua
Chongqing Medical University
Outcome results
None listed