Unexplained Recurrent Implantation Failure
Conditions
Interventions
high pNKC and normal pNKC group:none
High pNKC with oral prednisone treatment group:None
Normal pNKC with oral prednisone treatment group:None
Sponsors
Guangxi Reproductive Medical Center, the First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Aged 20 to 40 years; 2. Diagnosed as URIF; 3. The chromosomes of spouse are normal.
Exclusion criteria
Exclusion criteria: 1. Patients refused to sign the informed consent form; 2. Patients with luteal insufficiency, abnormal thyroid function, diabetes, prolactinoma and autoimmune diseases; 3. Patients with bilateral hydrosalpinx visible under ultrasound without ligation; 4. Patients with genital tract malformations and chronic endometritis; 5. Patients with endometriosis, uterine fibroids, intrauterine adhesions (including previous intrauterine adhesion separation) 6. Patients with prethrombotic state; 7. Patients weith endometrial scraping and intrauterine perfusion in the embryo transfer cycle; 8. Patients with bad habits such as smoking, alcohol abuse, excessive coffee drinking, drug abuse, etc. 9. Unfavorable environmental factors, such as excessive exposure to harmful chemical substances, excessive exposure to radiation, etc. 10.Severe immediate allergy to the drug prednisone.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Live birth rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical pregnancy rate;Abortion rate;Embryo implantation rate; | — |
Countries
China
Contacts
Public ContactYang Yihua
Guangxi Reproductive Medical Center, the First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed