retina denaturation
Conditions
Interventions
experiment group:hESC RPC transplantation into subretinal
Sponsors
The First Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
Male
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. As subjects, patients signed informed consent; 2. Aged 18 to 50 years old, regardless of gender; 3. The definite diagnosis was (1) Retinal detachment. The retina was successfully restored 2 months after vitrectomy, but the visual acuity recovered poorly; (2) Retinitis pigmentosa (RP) is mainly rod cell degeneration; 4. Corrected visual acuity: BCVA <= 0.1; 5. There was no proliferative membrane and edema in the macula; 6. Refractive media did not affect the observation of fundus; 7. There were no other retinal and optic neuropathy.
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating women; 2. Ocular refractive media opacity (such as corneal leukoplakia, cataract, etc.); 3. Complicated with other fundus diseases (such as glaucoma, venous obstruction, etc.); 4. It is complicated with serious primary diseases and psychosis such as cardiovascular, liver, kidney and hematopoietic system; 5. Systemic or local application of other drugs affecting efficacy evaluation, such as glucocorticoid; 6. Those who have participated in other clinical trials in recent three months; 7. BCVA in contralateral eyes was better than that in operative eyes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| vision; | — |
Countries
China
Contacts
Public ContactLiu Yong
The First Affiliated Hospital of Army Medical University
Outcome results
None listed