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Comparison of efficacy and safety of fractional CO2 laser and manual fractional CO2 laser for the treatment of xanthelasma palpebrarum: A multicenter randomized split-face controlled trial

Comparison of efficacy and safety of fractional CO2 laser and manual fractional CO2 laser for the treatment of xanthelasma palpebrarum: A multicenter randomized split-face controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200056388
Enrollment
Unknown
Registered
2022-02-04
Start date
2022-02-01
Completion date
Unknown
Last updated
2024-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

xanthelasma palpebrarum

Interventions

treatment group:fractional CO2 laser
control group:manual fractional CO2

Sponsors

Department of Dermatology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Chinese patients aged from 18 to 80 years; 2. Diagnosed with XP; all subjects had symmetrical lesions bilaterally.

Exclusion criteria

Exclusion criteria: 1. Had received prior treatment for XD; 2. Had tendency to develop hypertrophic and/or keloid scars; 3. Had been noticeably tanned recently; 4. Photosensitive; 5. Had taken medications in the past two weeks that could induce photosensitivity; 6. Pregnant women.

Design outcomes

Primary

MeasureTime frame
XP lesion clearance rate;—

Secondary

MeasureTime frame
Patient satisfaction;Safety evaluation;—

Countries

China

Contacts

Public ContactZhao Yi

Department of Dermatology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University

zhaoyimd@mail.tsinghua.edu.cn+86 13718646181

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026