Type 2 diabetes
Conditions
Interventions
Treatment group:Vitamin D2 injection and standard hypoglycemic therapy
Control group:Standard hypoglycemic therapy and placebo injection
Sponsors
The Second Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
30 Years to 69 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 30 and 69 years, and with the duration of diabetes for 5 to 15 years; 2. No long-term outdoor activities and long-term living plan in tropical areas within 6 months after the start of the clinical trial; 3. Meet the diagnostic criteria of T2DM; 4. Voluntarily participate in this study and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with ketoacidosis and lactic acidosis in recent 1 month; 2. 25-(OH)D> 20ng/ml; 3. Patients who use drugs that may affect VD metabolism or vitamin D and its analogues; 4. Blood calcium > 11mg/dl (2.75 mmol/L); 5. Vitamin D overdose or poisoning; 6. Patients with history of urinary calculi and sarcoidosis; autoimmune diseases; severe liver function injury; tumor, parathyroid gland, hemocytopenia and other diseases; HIV antibody positive; peripheral neuropathy caused by other causes; other serious acute and chronic diseases or with abnormal laboratory examination, are not allowed to participating in this study; 7. Significant cognitive impairment, mental disorder or physical dysfunction that may affect the completion of research related projects; 8. Alcohol or drug abusers; 9. Allergic to the drugs used in the study protocol; 10. Pregnancy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 25 hydroxyvitamin D;FPG;FINS;Serum calcium and phosphorus;HbA1C;Fasting C-peptide; | — |
Countries
China
Contacts
Public ContactHu Ji
The Second Affiliated Hospital of Soochow University
Outcome results
None listed