postoperative analgesia
Conditions
Interventions
Intervention group:lidocaine spray
Control group:Placebo
Sponsors
Department of Anesthesiology, Peking University Hospital of Stomatology
Eligibility
Sex/Gender
All
Age
4 Years to 14 Years
Inclusion criteria
Inclusion criteria: 1. Aged 4 to 14 years old; 2. ASA I-II; 3. Velopharyngeal insufficiency, posterior pharyngeal flap surgery; 4. Enrolled in the study are all minor patients, and the guardian's consent is required to participate.
Exclusion criteria
Exclusion criteria: 1. Child has cognitive or neuropsychiatric diseases, and developmental delay; 2. Lidocaine and alcohol allergy; 3. Pharyngeal infection or suspected malignant tumor; 4. Have a history of asthma; 5. Long-term use of anticonvulsant, sedative and analgesic drugs; 6. Abnormal liver and kidney function; 7. Severe cardiovascular and cerebrovascular diseases, coagulation disorders; 8. Patients with severe sleep apnea (sleep apnea index>=5.0).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Compare the maximum pain scores of the two groups in patients during PACU; | — |
Secondary
| Measure | Time frame |
|---|---|
| The extubation time;Pain scores in different time periods of PACU (10min, 20min, 30min, 30min to exit PACU);The incidence of moderate to severe pain in PACU; The rescue opioids for PACU and 24 hours postoperatively, the time of first rescue ;Agitation score and incidence of delirium;Pain score for 24 hours ater surgery;The incidence of moderate to severe pain within 24 hours after leaving PACU;The rescue oral analgesics on the wards;The incidence of nausea and vomiting in PACU and wards;Time to resume eating;Postoperative hospital stay;Parent satisfaction (0-10 points);24h postoperative complications: respiratory complications (hypoxemia: blood oxygen saturation 30 seconds), bleeding, infection, secondary operations, etc.; | — |
Countries
China
Contacts
Public ContactZhou Dan
Peking University Hospital of Stomatology
Outcome results
None listed