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A single blind randomized controlled study on the analgesic effect of femoral nerve block combined with low concentration ropivacaine anterior sciatic nerve block or intra-articular local anesthetic injection after unilateral total knee arthroplasty

A single blind randomized controlled study on the analgesic effect of femoral nerve block combined with low concentration ropivacaine anterior sciatic nerve block or intra-articular local anesthetic injection after unilateral total knee arthroplasty

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200056371
Enrollment
Unknown
Registered
2022-02-04
Start date
2022-02-01
Completion date
Unknown
Last updated
2024-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total knee arthroplasty

Interventions

experiment group:Sciatic nerve block + femoral nerve block
control group:Intra articular local anesthetic injection+Intra-articular local anesthetic injection

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Unilateral total knee arthroplasty was planned; 2. Aged 60 to 80 years, weighted 50 to 90kg, ASA grade I - II; 3. Normal cognitive function; 4. The functions of heart, lung, liver and kidney were basically normal, and the patient had no clear contraindications; 5. Voluntarily join the study cohort and be able to cooperate to observe adverse events and curative effects; 6. Written informed consent signed by the patient or his legal representative; 7. The visit time is from October 2021 to October 2022.

Exclusion criteria

Exclusion criteria: 1. There are definite contraindications of nerve block (abnormal coagulation function, infection at puncture site, etc.): 2. Failure to cooperate to complete nerve block (patients with unconsciousness or mental abnormalities); 3. Hypersensitivity to ultrasound couplants, local anesthetics or opioids; 4. The general condition is poor and can not tolerate surgical treatment; 5. Long term oral analgesics; 6. Contraindication of spinal anesthesia 7. Other unsuitable candidates evaluated by clinicians.

Design outcomes

Primary

MeasureTime frame
VAS;

Secondary

MeasureTime frame
Lower limb muscle strength;Knee and ankle range of motion;

Countries

China

Contacts

Public ContactWang Liwei

Peking University Third Hospital

408670153@sina.com+86 15201304191

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026