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Effects of ischemic preconditioning on intracranial hemodynamics and prognosis in acute ischemic stroke patients with interventional treatment

Effects of ischemic preconditioning on intracranial hemodynamics and prognosis in acute ischemic stroke patients with interventional treatment

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200056368
Enrollment
Unknown
Registered
2022-02-04
Start date
2022-01-24
Completion date
Unknown
Last updated
2024-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Ischemic Stroke

Interventions

Intervention group:remote ischemic preconditioning
Sham controlled group:Sham controlled treament

Sponsors

The Second Affiliated Hospital of Shandong First Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged 18 years and over, regardless of gender; 2. Acute ischemic stroke was confirmed by DSA to be intracranial internal carotid artery (ICA) or middle cerebral motility Occlusion of artery (MCA) M1 / M2 or anterior cerebral artery (ACA) A1 / A2; 3. The patients were suitable for intravascular interventional therapy. The recanalization rate was confirmed by DSA after treatment, and mTICI score was >= 2b; 4. Pre onset mRS <= 1; 5. The patient or legal guardian signs the informed consent.

Exclusion criteria

Exclusion criteria: 1. Hemorrhagic stroke or mixed stroke; 2. Refractory hypertension beyond drug control, defined as systolic bp > 185mmHg or diastolic bp > 11mmHg; 3. History of hemorrhagic disease or cerebral hemorrhage systemic bleeding tendency or recent history of acute hemorrhagic disease; 4. There is known to be severe heart, lung, liver and kidney failure or other serious disease (such as an untreated intracranial swelling, aneurysms, intracranial aneurysms or arteriovenous malformations); 5. Patients with mental illness; 6. Pregnant or lactating women; 7. The researcher judged that there were other conditions that were not suitable for the group; 8. History of upper limb disability or new trauma severe upper limb infection, upper limb deep venous thrombosis limb thrombophlebitis limb or existing history of severe trauma; 9. The researchers found it inappropriate to participate in the study.

Design outcomes

Primary

MeasureTime frame
mRS;Blood flow velocity of responsible artery and contralateral artery;blood biochemical indexes;PI of responsible artery;NIHSS score;

Countries

China

Contacts

Public ContactZhang Yanbo

The Second Affiliated Hospital of Shandong First Medical University

bbnnbn@163.com+86 13053872839

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026