Clinical study of glucocorticoid for postoperative analgesia after rhinoplasty with autologous costal cartilage transplantation

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200056352

Enrollment

Unknown

Registered

2022-02-04

Start date

2022-02-07

Completion date

Unknown

Last updated

2024-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rhinoplasty with autologous costal cartilage

Interventions

Group C:ropivacaine, parecoxib and epinephrineanalgesia

Group A:ropivacaine, parecoxib, betamethasone and epinephrineanalgesia

Group B:ropivacaine, parecoxib, triamcinolone and epinephrineanalgesia

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients requiring initial rhinoplasty with autologous costal cartilage; 2. Aged 18 to 60 years; 3. Body mass index was 20-35 kg/m2; 4. The American Society of Anesthesiologists (ASA) classification (anesthesia risk assessment) is I - III level; 5. The patient signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Alcohol or drug abuse and and allergic to any drugs in this trial; 2. Long-term opioid users(opioids were used daily or almost daily for more than 3 months); 3. Language impairment and inability to perform pain numerical scales (NRS); 4. Local skin infection and bleeding at the puncture site of anesthesia; 5. Patients considered unfit for inclusion by the surgeon or anesthesiologist.

Design outcomes

Primary

Measure	Time frame
VAS pain score;	—

Secondary

Measure	Time frame
Oral analgesics;Nausea and vomiting;Itchy skin;	—

Countries

China

Contacts

Public ContactFan Fei

Peking Union Medical College Plastic Hospital

fanfei@psh.pumc.edu.cn+86 13311231331

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026