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Effect of quadratus lumbosum block on acute kidney injury after laparoscopic radical nephrectomy for renal carcinoma

Effect of quadratus lumbosum block on acute kidney injury after laparoscopic radical nephrectomy for renal carcinoma

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200056342
Enrollment
Unknown
Registered
2022-02-04
Start date
2022-02-07
Completion date
Unknown
Last updated
2024-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury

Interventions

Group QLB:Before surgery, quadratus lumborum muscle block was performed on the operative side
control group:No intervention

Sponsors

The Third Medical Center of Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients who received laparoscopic radical nephrectomy under general anesthesia in our hospital; 2. Aged 40 to 75 years old; 3. ASA grades I-II; 4. Body mass index (BMI)<40kg/m^2; 5. Liver and kidney function are normal before surgery.

Exclusion criteria

Exclusion criteria: 1. Severe heart, lung and brain diseases; 2. Patients without informed consent; 3. Patients with serious complications during surgery; 4. Abnormal coagulation function; 5. Contraindications of quadratus lumborum block (QLB).

Design outcomes

Primary

MeasureTime frame
Scr;Urine volume;—

Secondary

MeasureTime frame
Opioid Use Level;Visual analogue scale;Times of postoperative relief analgesia;Malondialdehyde, MDA;Advanced oxidative protein product, AOPP;GSH-PX;Nrf2;Antioxidant response elements;—

Countries

China

Contacts

Public ContactZhang Ling

Anesthesia Department of the Third Medical Center of PLA General Hospital

249948341@qq.com+86 13522981008

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026