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Internal jugular vein incompetence and primary cough headache: A case control research

Internal jugular vein incompetence and primary cough headache: A case control research

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200056331
Enrollment
Unknown
Registered
2022-02-04
Start date
2022-02-10
Completion date
Unknown
Last updated
2024-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

primary cough headache

Interventions

Case group:None
Control group:None

Sponsors

International Headache Center, Department of Neurology, Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for case group: 1. Aged 18 to 65 years old (65 included); 2. Primary headache; 3. (1) At least two headache episodes fulfilling criteria (2)–(4); (2) Brought on by and occurring only in association with coughing, straining and/or other Valsalva movement; (3) Sudden onset; (4) Lasting between one second and two hours; (5) Not better accounted for by another ICHD-3 diagnosis. Inclusion criteria for control group: 1.Aged 18 to 65 years old (65 included); 2.No headache.

Exclusion criteria

Exclusion criteria: Exclusion criteria for case group: 1. Secondary cough headache, such as Chiari malformation type 1, middle cranial fossa and post cranial fossa tumor, midbrain cyst, skull base depression, skull base flattering, subdural hematoma, carotid or vertebrobasilar artery abnormalities, aneurysms, RCVS, intracranial hypotension and other intracranial organic pathology; 2. Comorbidity with other type of headache; 3. Unwilling or unable for internal jugular vein ultrasound examination; 4. Vulnerable people, such as pregnant woman, unable for informed consent due to cognitive deficit or other disease status, employee or student of fellow researchers and leader of study and patient with terminal stage disease. Exclusion criteria for control group: 1. Vulnerable people, such as pregnant woman, unable for informed consent due to cognitive deficit or other disease status, employee or student of fellow researchers and leader of study and patient with terminal stage disease.

Design outcomes

Primary

MeasureTime frame
Reverse blood flow peak velocity;

Countries

China

Contacts

Public ContactYu Shengyuan

Chinese PLA General Hospital

naweinan1996@sina.com+86 10 55499118

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026