primary cough headache
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria for case group: 1. Aged 18 to 65 years old (65 included); 2. Primary headache; 3. (1) At least two headache episodes fulfilling criteria (2)–(4); (2) Brought on by and occurring only in association with coughing, straining and/or other Valsalva movement; (3) Sudden onset; (4) Lasting between one second and two hours; (5) Not better accounted for by another ICHD-3 diagnosis. Inclusion criteria for control group: 1.Aged 18 to 65 years old (65 included); 2.No headache.
Exclusion criteria
Exclusion criteria: Exclusion criteria for case group: 1. Secondary cough headache, such as Chiari malformation type 1, middle cranial fossa and post cranial fossa tumor, midbrain cyst, skull base depression, skull base flattering, subdural hematoma, carotid or vertebrobasilar artery abnormalities, aneurysms, RCVS, intracranial hypotension and other intracranial organic pathology; 2. Comorbidity with other type of headache; 3. Unwilling or unable for internal jugular vein ultrasound examination; 4. Vulnerable people, such as pregnant woman, unable for informed consent due to cognitive deficit or other disease status, employee or student of fellow researchers and leader of study and patient with terminal stage disease. Exclusion criteria for control group: 1. Vulnerable people, such as pregnant woman, unable for informed consent due to cognitive deficit or other disease status, employee or student of fellow researchers and leader of study and patient with terminal stage disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reverse blood flow peak velocity; | — |
Countries
China
Contacts
Chinese PLA General Hospital