PCOS
Conditions
Interventions
Experiment group:Dual trigger
Sponsors
The First Affiliated Hospital of Choqnging Medical University
Eligibility
Sex/Gender
Female
Age
20 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. Patients who received treatment for the first time GnRH antagonist program-controlled excretion ART (IVF/ICSI) in the Reproductive Medicine Center of the First Affiliated Hospital of Chongqing Medical University and Chongqing Maternal and Child Health Hospital from March 2022 to February 2023; 2. Female subjects between 20 and 35 years old; 3. Patients diagnosed with PCOS (PCOS diagnostic criteria: clinical or laboratory hyperandrogenism; rare ovulation or anovulation; >= 12 small follicles with a diameter of 2-9 mm on one or both ovaries on ultrasound examination; If 2 of the above 3 items are met, and other hyperandrogen diseases are excluded, PCOS can be diagnosed); 4. For the first time, subjects using GnRH antagonist regimen controlled ART (IVF/ICSI); 5. Subjects who are willing to participate in and abide by the protocol during the research period; 6. Subjects who have obtained informed consent before proceeding with any procedures related to the research.
Exclusion criteria
Exclusion criteria: 1. Abnormal chromosome karyotype; 2. Any contraindications to pregnancy and/or childbirth; 3. Subjects suffering from systemic diseases (such as diabetes, hypertension, abnormal thyroid function, etc.); 4. Endometriosis, hydrosalpinx, uterine malformations, intrauterine adhesions; 5. Repeated implantation failures (3 or more embryo transfers or cumulative transfers of more than 4 high-quality embryos, all failed to become pregnant); repeated failure to promote ovulation (previously more than 2 ovulation cycles).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| number of oocyte retrieved;available embryo number;OHSS rate (moderate-severe); | — |
Secondary
| Measure | Time frame |
|---|---|
| MII oocyte rate;Number of high quality embryo;Biochemical pregnancy rate;Clinical pregnancy rate;Ongoing pregnancy rate; | — |
Countries
China
Contacts
Public ContactHuang Jiayu
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed