Sepsis, septic shock
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: According to the sepsis diagnostic criteria: clinical infection or suspicion of infection, and SOFA score >= 2. Septic shock: preexisting sepsis with circulatory swings after adequate volume resuscitation, vasoactive medications still required to maintain MAP >= 65 mmHg, and blood lactate levels > 2 mmol / L.
Exclusion criteria
Exclusion criteria: 1. Age < 18 years; 2. Those with untreated tumors; 3. Raynaud syndrome; 4. Severe peripheral vasculopathy; 5. Those with contraindications to central venous and femoral catheterization; 6. Advanced patients who cannot be treated with fluid resuscitation; 7. Pregnant or gestational patients; 8. Those with poor adherence to treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate;Mean arterial pressure;Central venous pressure;Central venous blood oxygen saturation;Lactate;Liquid negative equilibrium time;ICU length of stay; | — |
Countries
China
Contacts
The Affiliated Hospital of Hangzhou Normal University