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Relationship between the metabolites of flavanols and gestational diabetes mellitus and the mechanism mediated by NLRP3 inflammasome

Relationship between the metabolites of flavanols and gestational diabetes mellitus and the mechanism mediated by NLRP3 inflammasome

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200056287
Enrollment
Unknown
Registered
2022-02-03
Start date
2020-05-01
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gestational Diabetes Mellitus

Interventions

GDM group:None
normal pregnant group:None

Sponsors

Shenzhen Nanshan District People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Case group: Singleton pregnant women aged between 20 and 45 at 0-12 weeks of gestation; Meets the diagnostic criteria of GDM. Control group: 1:1 individual matching was conducted with the case group, with the matching criteria being normal pregnant women of the same gender, with an age difference of less than 2 years, and a BMI difference of less than 1kg/m2.

Exclusion criteria

Exclusion criteria: Case group: People who with type 1 or type 2 diabetes; Hepatitis, syphilis, AIDS and other infectious diseases; IVF, placental abruption, preeclampsia, patients with hyperthyroidism or chronic diseases such as liver and kidney, intellectual abnormalities, physical disabilities. Control group: Meets the diagnostic criteria of GDM, other exclusion criteria are the same as the case group.

Design outcomes

Primary

MeasureTime frame
Flavanol;Blood glucose;—

Countries

China

Contacts

Public ContactGuifang Deng

Shenzhen Nanshan District People's Hospital

misyfly@163.com+86 135 4428 0781

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026