Clinical study of microcirculatory parameters in septic/septic shock patients treated with Oxiris filter

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200056282

Enrollment

Unknown

Registered

2022-02-03

Start date

2022-02-07

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis/septic shock

Interventions

experimental group:Use the oXiris filter

control group:Use the standard filter

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients who meet the definition and diagnostic criteria of sepsis, septic shock 3.0; 2. Patients aged >= 18 years; 3. Patients with AKI requiring CRRT; 4. Obtain informed consent.

Exclusion criteria

Exclusion criteria: 1. patients also suffer from other serious life-threatening diseases, such as malignant tumors, severe bleeding disorders or immunosuppressive related diseases; 2. patients admitted to ICU < 48h; 3. pregnant or lactating female patients; 4.4 or 5 stage chronic kidney disease or maintenance dialysis treatment; 5. patients with renal artery stenosis; 6. patients with sublingual mucosal damage, difficulty in opening the mouth or combined oral diseases and sublingual microcirculation collection is not possible;

Design outcomes

Primary

Measure	Time frame
Sublingual microcirculation parameters;Renal resistance index;Cytokines;	—

Countries

China

Contacts

Public ContactLin Changcheng

The First Affiliated Hospital, Sun Yat-Sen University

lilifengz@163.com+86 138 2228 1788

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026