colonic cancer
Conditions
Interventions
Group A:Morning surgery + total intravenous anesthesia group
Group B:Morning surgery + inhalation anesthesia group
Group C:Afternoon surgery + total intravenous anesthesia group
Group D:Afternoon surgery + inhalation anesthesia group
Sponsors
Cancer hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: ASA I-III, aged 18-80 years, body mass index (BMI) 18-30, patients undergoing laparoscopic carbon dioxide pneumoperitoneum radical colon cancer surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: 1. Patients with inflammatory diseases; 2. Patients who have received surgical treatment in the past 30 days; 3. Pregnant women; 4. Patients with renal diseases; 5. Long-term use of psychotropic drugs such as sedatives or antidepressants; 6. Difficulty in understanding language, mental illness, inability to visit hospitals for follow-up, etc.; 7. History of previous abdominal surgery, endocrine and immune system diseases (diabetes, thyroid disease, rheumatism, etc.), Crohn's disease and ulcerative colitis, preoperative hormones and non-steroids Anti-inflammatory and analgesic drugs that affect the immune function of the body and patients who receive radiotherapy and chemotherapy before surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neutrophil/lymphocyte ratio;CRP;Th17 cell;interleukin-22 level of the intestinal local tissue; | — |
Countries
China
Contacts
Public ContactTian Naiyuan
Cancer hospital, Chinese Academy of Medical Sciences
Outcome results
None listed