Chronic refractory wounds
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with basic medical diseases who are in stable condition after standardized medical diagnosis and treatment after admission; 2. After wound dressing change, debridement and negative pressure sealing drainage for at least 4 weeks, the wound showed no signs of improvement or aggravating trend; 3. Patients who have not used immunosuppressants and have not taken anticoagulants recently.
Exclusion criteria
Exclusion criteria: 1. Patients with mental illness, lack of insight and unable to express themselves accurately, and those with poor compliance; 2. Patients with blood disease, serious cardiovascular disease and sepsis; 3. Hemoglobin < 110 g / L, platelet PLT < 50 x 10^9/L, hematocrit < 33%; 4. Pregnant and lactating women; 5. Thrombin allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area of the unhealed wound size;Time of wound healing; | — |
Countries
China
Contacts
The Affiliated Hospital of Qingdao University