Benign prostatic hyperplasia
Conditions
Interventions
Sufentanil + esticketamine:Compound esticketamine
Sufentanil:Postoperative analgesia with sufentanil
Sponsors
Shunde Hospital, Southern Medical University
Eligibility
Sex/Gender
Male
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. 65-85 years old; 2. Qualified for American society of anesthesiologists classification (ASA) class I-II; 3. Body mass index < 30kg/m^2; 4. Preoperative assessment of liver and kidney function and coagulation were normal.
Exclusion criteria
Exclusion criteria: 1. Poorly controlled or untreated hypertension (arterial hypertension, resting systolic/diastolic blood pressure over 180/100 mmHg, 1 mmHg=0.133 kPa) in patients with severe cardiovascular and cerebrovascular diseases; 2. Contraindications of spinal anesthesia; 3. Patients with preoperative mental disorder (including preoperative Zung Depression Self-rating Scale score >=50); 4. Preoperative sleep disorder; 5. Intraoperative TURP syndrome; 6. Intracranial pressure, intraocular pressure increased; 7. Long-term or recent use of sedatives, analgesics, non-steroidal drugs, glucocorticoid drugs, psychotropic drugs, alcoholism, drug users; 8. Allergic to any of the drug ingredients in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sleep quality; | — |
Countries
China
Contacts
Public ContactYiwen Zhang
Shunde Hospital, Southern Medical University
Outcome results
None listed