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Basic and clinical study of scopolamine extracted from Flos Lonicerae in the treatment of perioperative pain syndrome

Basic and clinical study of scopolamine extracted from Flos Lonicerae in the treatment of perioperative pain syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200056236
Enrollment
Unknown
Registered
2022-02-02
Start date
2022-04-01
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative chronic pain syndrome

Interventions

Esketamine group:Intravenous use of esketamine
Sufentanil group:Intravenous use of sufentanil
Scopolamine group:Intravenous use of scopolamine

Sponsors

Xuzhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged between 30 and 75 years (including 30 and 75 years old); 2. American Society of anesthesiologists (ASA) grade I and II; 3. Patients undergoing thoracoabdominal surgery under general anesthesia.

Exclusion criteria

Exclusion criteria: 1. Preoperative abnormal liver and kidney function (preoperative liver enzyme index or creatinine exceeded the upper limit of normal by 1.5 times); 2. Heart failure; 3. Arrhythmia; 4. Morbid obesity; 5. Bronchial asthma; 6. Abnormal coagulation function; 7. History of cerebrovascular accidents, increased intracranial pressure, and intracranial space-occupying lesions; 8. Patients with previous dependence or allergy to analgesic and narcotic drugs; 9. Unable to cooperate for various reasons.

Design outcomes

Primary

MeasureTime frame
Visual Analogue Scale;Postoperative recovery evaluation QoR-40;—

Countries

China

Contacts

Public ContactHai Zhou

Xuzhou Central Hospital

zhouhai339339@163.com+86 18952171368

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026