Clinical study on the correlation between chronic ejection fraction retention heart failure and frailty in the elderly

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200056233

Enrollment

Unknown

Registered

2022-02-02

Start date

2022-02-01

Completion date

Unknown

Last updated

2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart failure, fatigue

Interventions

case series:None

Eligibility

Sex/Gender

All

Age

60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Elderly heart failure patients, male and female, >= 60 years old were enrolled; 2. Meet the diagnostic criteria of HFpEF in the Chinese Guidelines for the Diagnosis and Treatment of Heart failure 2018; (1) Have symptoms or signs of heart failure, and have no acute heart failure in recent 1 month; (2) LVEF >= 50%, NYHA cardiac function grade II ~IV; (3) NT-probNP >125ng/L, and conform to one of the following: 1) Left ventricular hypertrophy/left atrium enlargement; 2) Cardiac diastolic dysfunction.

Exclusion criteria

Exclusion criteria: 1. Mitral stenosis or aortic stenosis and other severe valvular heart disease; 2. Acute myocardial infarction; 3. Acute pericarditis, rheumatic heart disease, etc.; 4. Thrombophlebitis or intracardiac thrombosis; 5. Severe complications, advanced malignant tumor, life expectancy <6 months; 6. Those who refuse or cannot accept the evaluation.

Design outcomes

Primary

Measure	Time frame
Fatigue index;Pro-BNP;Albumin;LVEF;	—

Countries

China

Contacts

Public ContactWang Xiangming

The First Affiliated Hospital of Nanjing Medical University

wangxiangming@jsph.org.cn+86 13813992936

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026