Nasopharyngeal carcinoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The pathological results of all patients after one-stage radiotherapy showed local recurrence of the nasopharynx; 2. Preoperative MRI showed that the recurrent lesions were limited to the nasopharynx, slightly invading the anterior styloid space or involving the bottom of the sphenoid bone, and there was sufficient safe boundary (more than 1 cm from the ipsilateral internal carotid artery); 3. Aged between 18-75; 4. The distance between anterior incisors exceeds 4.0cm.
Exclusion criteria
Exclusion criteria: 1. Extensive skull base bone destruction or cranial nerve paralysis; 2. Cervical lymph node metastasis or distant metastasis; 3. Patients with limited mouth opening or closed teeth; 4. Patients with poor general basic conditions or unable to tolerate general anesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Locoregional relapse-free survival (LRFS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall Survival (OS);Progression Free Survival (PFS);Locoregional Recurrence Free Survival (LRFS); | — |
Countries
China
Contacts
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University