Autoimmune disease
Conditions
Interventions
rheumatoid arthritis:N/A
systemic sclerosis:N/A
idiopathic inflammatory myositis:N/A
Sjogrens syndrome:N/A
ankylosing spondylitis:N/A
Gout:N/A
Sponsors
Department of Rheumatology and Immunology, the First Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients voluntarily participate in this study and sign the informed consent form. 2. Patients aged 18-60 years who are diagnosed with systemic lupus erythematosus according to the 2009ACR standard or 2019EULAR/ACR standard, patients who were diagnosed with systemic sclerosis according to the 2013ACR/EULAR standard, and were diagnosed as class according to the 2010ACR/EULAR standard Patients with rheumatoid arthritis, patients diagnosed with idiopathic inflammatory myopathy according to 2017 ACR/EULAR criteria or Bohan/Peter criteria in 1975, patients diagnosed with primary Sjogrens syndrome according to 2016 ACR/EULAR criteria, Patients who were diagnosed with ankylosing spondylitis according to the 2009ASAS criteria, and patients who were diagnosed with gouty arthritis according to the 2015ACR/EULAR criteria.
Exclusion criteria
Exclusion criteria: 1. Petients with metal implants, pacemakers and other implants in the body, residual ferromagnetic materials such as shrapnel, and non-removable dentures; 2. Patients with intracranial lesions, or a history of confirmed intracranial lesions (including but not limited to cerebral infarction, cerebral hemorrhage, intracranial space occupation, intracranial vascular malformations, etc.), patients with heart disease or previously diagnosed cardiovascular diseases (including but not limited to coronary heart disease, valvular heart disease, cardiomyopathy, etc.); 3. Have a history of craniocerebral trauma; 4. Past routine MRIs suggest brain atrophy or structural abnormalities; 5. Have a history of neuropsychiatric disease or a family history of mental diseases; 6. Severe organ involvement with other chronic diseases; 7. Pregnancy; 8. History of alcohol or drug abuse; 9. Fear of claustrophobia or allergy to contrast agents; 10. Other special circumstances that cannot cooperate to complete the inspection (such as unable to continue lying supine, etc.); 11. Situations were considered unsuitable for participation by other researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Imaging of head;Imaging of heart; | — |
Secondary
| Measure | Time frame |
|---|---|
| Symptoms and signs;Laboratory indicators;Molecular indicators;Genetic indicators;Mental scales; | — |
Countries
China
Contacts
Public ContactJian Xu
Department of Rheumatology and Immunology, the First Affiliated Hospital of Kunming Medical University
Outcome results
None listed