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Correlation and mechanism of exposure to typical organic pollutants and risk of coronary artery disease

Correlation and mechanism of exposure to typical organic pollutants and risk of coronary artery disease

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200056188
Enrollment
Unknown
Registered
2022-02-01
Start date
2022-02-10
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary atherosclerotic heart disease

Interventions

Group of coronary heart disease:None
Group of non coronary heart disease:None

Sponsors

The Second Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 79 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria of case group: 1. Meet the diagnostic criteria for coronary heart disease formulated by the American Heart Association; 2. The patient's clinical manifestations, myocardial zymogram or ECG changes are consistent with the diagnostic criteria of coronary heart disease, or coronary angiography shows that the stenosis degree of at least one of its main coronary arteries is >= 50%; 3. Sign the informed consent form and be willing to cooperate with this study. Inclusion criteria of control group: 1. Patients without typical clinical symptoms and normal ECG or color Doppler echocardiography, who are judged by doctors as non coronary heart disease; 2. Sign the informed consent form and be willing to cooperate with this study.

Exclusion criteria

Exclusion criteria: 1.Subjects with previous severe valvular disease, severe myocarditis, severe liver and kidney damage, severe infectious diseases, blood diseases, thyroid dysfunction, tumors; 2.Missing clinical data.

Design outcomes

Primary

MeasureTime frame
Per- and polyfluoroalkyl substances;Phthalate esters and their metabolites;Triphenyl phosphate and its metabolites;Halogenated organics;Polycyclic aromatic hydrocarbons;Halogenated flame retardant;

Countries

China

Contacts

Public ContactGuo huicai

The Second Hospital of Hebei Medical University

huicaiguo@hotmail.com+86 18931108951

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026