Skip to content

Comparison of the onset time and effect of epidural anesthesia for cesarean section with two drug regimens

Comparison of onset time and effect of chloroprocaine and lidocaine carbonate combined with fentanyl in epidural anesthesia for cesarean section

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200056180
Enrollment
Unknown
Registered
2022-02-01
Start date
2022-02-08
Completion date
Unknown
Last updated
2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epidural anesthesia for cesarean section

Interventions

Group CP:15ml of 3% chloroprocaine
Group LF:15ml of 1.73% lidocaine carbonate combined with 50µg of fentanyl

Sponsors

Xiaoshan Hospital Affiliated to Hangzhou Normal University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. ASA I - II; 2. Aged 18-40 years; 3. 150cm = 37 weeks; 5. Caesarean section is scheduled; 6. Patients signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Allergic to drugs used in this study; 2. Spinal deformity; 3. Twin and/or multiple pregnancies; 4. Coagulation dysfunction; 5. Infection at the puncture site; 6. Complicated with gestational diseases (such as gestational hypertension, gestational diabetes, etc.).

Design outcomes

Primary

MeasureTime frame
The time from injection of Initial epidural induction dose to T6 of block level;

Secondary

MeasureTime frame
The time from injection of Initial epidural induction dose to T8 of block level;Incidence of administering additional epidural doses;Incidence of esketamine remediation;The incidence of hypotension;Apagr score of neonates;Bromage scores;Patient satisfaction;The highest level of nociceptive block;The incidence of nausea and vomiting;

Countries

China

Contacts

Public ContactJing Yu

Xiaoshan Hospital Affiliated to Hangzhou Normal University

yujing7274@126.com+86 18967168531

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026