Hypotension
Conditions
Interventions
Group P:phenylephrine 50µg
Group N:norepinephrine 4µg
Sponsors
Women's Hospital School of Medicine Zhejiang University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Single fetus PE patients who plan to perform elective cesarean section and choose combined spinal epidural anesthesia; 2. ASA Level 2-3; 3. Aged 18-40 years; 4. Obtain ethical permission and informed consent of patients before the experiment; 5. The diagnostic criteria of preeclampsia are: blood pressure >= 140/90mmhg, measurement interval at least 4 hours, 24-hour proteinuria = 300mg or test paper proteinuria >= 1+.
Exclusion criteria
Exclusion criteria: 1. Patients with chronic hypertension, diabetes and serious cardiovascular and cerebrovascular diseases; 2. Patients with known fetal abnormalities or intrauterine growth restriction; 3. Patients with obstetric complications include premature rupture of membranes, placenta previa and placental abruption; 4. Those who have contraindications to intraspinal anesthesia or research related drugs; 5. The patient's clinical ASA grade is more than 3; 6. The height is too high or too low (>180 cm or<150 cm); 7. Gestational age < 28 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulsatility Index; | — |
Countries
China
Contacts
Public ContactFeng Fu
Women's Hospital School of Medicine Zhejiang University
Outcome results
None listed