Effect of dexmedetomidine on the prevention and treatment of post-traumatic stress disorder after emergency trauma

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200056162

Enrollment

Unknown

Registered

2022-02-01

Start date

2022-02-01

Completion date

Unknown

Last updated

2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-traumatic stress disorder

Interventions

experimental group:Intravenous pumping of dexmedetomidine

control group:normal saline

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Emergency trauma: car accident, falling, engineering accident, etc.; 2. ASA I - III; 3. Aged 18-60 years.

Exclusion criteria

Exclusion criteria: 1.Craniocerebral or spinal cord injury,hemorrhagic shock decompensation. 2.Liver or renal dysfunction; 3.History of alcohol abuse or drug dependence, history of neurological or psychiatric diseases; 4.Severe visual, hearing or language impairment; 5.history of major physical or mental trauma, severe atrioventricular block and sinus bradycardia.

Design outcomes

Primary

Measure	Time frame
PCL-5 scale score;The Clinician-Administered PTSD Scale for DSM–5;	—

Secondary

Measure	Time frame
Pain;Delirium;Nausea;Itching;	—

Countries

China

Contacts

Public ContactYangzi Zhu

Xuzhou Central Hospital

zhuyz@188.com+86 15862149539

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 9, 2026