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Transcranial direct current stimulation improves prospective memory in patients on the schizophrenia spectrum: a randomized controlled study

Transcranial direct current stimulation improves prospective memory in patients on the schizophrenia spectrum: a randomized controlled study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200056142
Enrollment
Unknown
Registered
2022-02-01
Start date
2022-02-01
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia spectrum

Interventions

Sponsors

Beijing Anding Hospital Affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Patients meeting DSM-5 criteria for schizophrenia; 2. Patients aged 18-50 years, with right handedness; 3. Junior high school or above, with IQ > 70; 4. Patients with PANSS score at most 5 in the following items: P1 delusion, P3 hallucination, P5 exaggeration, P6 suspicion/victimization, G9 abnormal thinking content; PANSS score at most 4 in the following item: P2 concept disorder; 5. Patients who are clinically stable, maintained on current antipsychotic and concomitant medications for at least 6 weeks, with no change in antipsychotic dose for at least 2 weeks. Patients must take the same type and dose of antipsychotic medications during the study period; 6. The patient and guardian sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Current severe somatic or neurological disease; 2. Current serious abnormalities in blood biochemical indicators, EEG or ECG; 3. Those who are extremely excitable, impulsive, or uncooperative; 4. Persons considered by the investigator to be at high risk of suicide or violence; 5. Those who have received electroconvulsive or magnetic stimulation therapy within six months; 6. Cochlear implant devices or other metal implants in the body; 7. Women who are pregnant or breastfeeding.

Design outcomes

Primary

MeasureTime frame
Change in subscale of Clue unfocused prospective memory combined with eye-tracking technology;

Secondary

MeasureTime frame
Change in subscale of Matrics Consensus Cognitive Battery (MCCB) scores;Change in subscale of Positive And Negative Syndrome Scale (PANSS) scores;Adverse effects of transcranial direct current stimulation (tDCS);

Countries

China

Contacts

Public ContactChuanyue Wang

Beijing Fengtai District Psychiatric Hospital

wang.cy@163.net+86 13910909974

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026