A prospective and historical comparative study of Proceed mesh combined with extraperitoneal fistulostomy in the prevention of parastomal hernia after abdominoperineal resection of rectal cancer

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200056134

Enrollment

Unknown

Registered

2022-02-01

Start date

2022-02-01

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

parastomal hernia

Interventions

Experimental group:Proceed mesh combined with extraperitoneal fistulostomy after abdominoperineal resection

Control group:APR surgery and direct transperitoneal permanent stoma

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged from 18 to 75 years; 2. Due to the condition, APR surgery is planned; 3. ASA <= III; 4. Patients can understand the study plan and are willing to participate in this study, provide written informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with intestinal obstruction, intestinal perforation, intestinal bleeding, etc.; 2. Severe psychiatric history; 3. Continuous systemic steroid therapy within 1 month; 4. Life expectancy < 2 years; 5. Patients who have undergone colostomy for reasons other than rectal cancer surgery.

Design outcomes

Primary

Measure	Time frame
Incidence of para-stomal hernia;	—

Secondary

Measure	Time frame
Incidence of other complications;	—

Countries

China

Contacts

Public ContactWang Ziqiang

West China Hospital of Sichuan University

Wangziqiang@scu.ecu.cn+86 18980602028

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026