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Prediction of the clinical outcome of intense pulsed light treatment in dry eye disease associated to meibomian gland dysfunction

Prediction of the clinical outcome of intense pulsed light treatment in dry eye disease associated to meibomian gland dysfunction

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200056131
Enrollment
Unknown
Registered
2022-02-01
Start date
2022-02-01
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eye

Interventions

Observation group:None

Sponsors

Eye Hospital and School of Ophthalmology and Optometry Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. 18 years old or above; 2. Meet the diagnostic criteria of dry eye. The standard mainly refers to the consensus of clinical diagnosis and treatment experts on dry eye proposed by the ophthalmology branch of Chinese Medical Association in 2013, that is, it has one of the symptoms such as dryness, foreign body sensation and vision fluctuation, BUT <= 5 s, or Schirmer I test (no surface anesthesia) <= 5 mm/ 5 min; 5 s < BUT <= 10 s or 5 mm/ 5 min < Schirmer I test (no surface anesthesia) <= 10 mm/ 5 min, with positive staining of corneal conjunctival fluorescein; 3. It meets the diagnostic criteria of MGD in China: dry eye symptoms with abnormal blepharal fat secretion or one of the following morphological abnormalities of the lower eyelid margin: (1) Hyperemia and telangiectasia of the eyelid margin; (2) Hyperkeratosis of the eyelid margin; (3) Hypertrophy of the eyelid margin; (4) Irregular shape of the eyelid margin; (5) Neovascularization of the eyelid margin; 4. The treatment scheme of IPL combined with meibomian gland massage (MGX) has been completed for four times; 5. Dry eye examination was completed before treatment, 1 month and 3 months after treatment.

Exclusion criteria

Exclusion criteria: 1. Other eye diseases other than cataract; 2. History of eye surgery or trauma, excluding meibomian gland cyst resection; 3. Incomplete closure of eyelids; 4. Acute ocular inflammation; 5. History of pregnancy or systemic immune system diseases; 6. Contact lens wearers within 2 weeks before or during treatment; 7. A history of systemic or ocular drug use affecting tear film is known within 2 weeks before or during treatment.

Design outcomes

Primary

MeasureTime frame
tear break-up time, TBUT;standard patient evaluation of eye dryness, SPEED;

Countries

China

Contacts

Public ContactYana Fu

Eye Hospital and School of Ophthalmology and Optometry Wenzhou Medical University

27771310@qq.com+86 13003605152

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026