Narcotic sedative drug
Conditions
Interventions
L group:Remimazolam was pumped 6 mg/kg/h during induction of anesthesia
M group:Remimazolam was pumped 9 mg/kg/h during induction of anesthesia
H group:Remimazolam was pumped 12 mg/kg/h during induction of anesthesia
Sponsors
Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1. Patients under general anesthesia for elective unilateral arthroscopic surgery; 2. Aged 18-64 years, regardless of gender; 3. BMI 18-30 kg/m^2; 4. Normal communication; 5. ASA grade I-II; 6. Voluntary subjects signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe cardiopulmonary system diseases; 2. Endocrine system diseases: pituitary tumor, severe diabetes, increased cortisol syndrome, pheochromocytoma and other; 3. Mental diseases: schizophrenia, depression, chronic analgesic drug use, alcoholism, opioid dependence; 4. Parkinson's disease, cerebral infarction, Alzheimer's disease, severe insomnia; 5. Inability to understand 15-item Quality of Recovery (QOR-15); 6. Preoperative life was not able to take care of themselves; 7. Hemorrhagic disease history or abnormal coagulation function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The time it took for bispectral index (BIS) to fall to 60; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bispectral index (BIS) down to 60, the dose of remimazolam;Hemodynamic parameters;15-item Quality of Recovery, QoR-15;Adverse reaction; | — |
Countries
China
Contacts
Public ContactLu Yao
Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical University
Outcome results
None listed