Hypoxemia
Conditions
Interventions
Propofol group:Propofol 1.5 mg/kg for sedation induction
Rimazolam group:Rimazolam 5.0 mg for sedation induction
Sponsors
Qilu Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. 60 years old <= age < 80 years old; 2. Painless gastroscopy is performed; 3. Patient or family informed consent; 4. ASA classification I-II.
Exclusion criteria
Exclusion criteria: 1. Those with nasal bleeding, nasal mucosal injury, nasal occupancy, etc. who are unable to perform transnasal CO2 monitoring; 2. Patients with diagnosed heart disease (heart failure, angina, heart attack, arrhythmia, etc.); 3. Diagnosed lung disease (asthma, bronchitis, COPD, pulmonary aspergillosis, pulmonary embolism, lung cancer, etc.); 4. Pre-existing hypotension (systolic blood pressure <= 90 mmHg), bradycardia (heart rate < 50 beats/min) or hypoxemia (SaO2 < 90%); 5. The presence of underlying diseases requiring oxygenation; 6. Emergency surgery; 7. Multiple trauma; 8. Clear upper respiratory tract infection; 9. Allergy to sedative drugs such as propofol or equipment such as tape.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate;Blood pressure;Pulse Oxygen Saturation;Drug Dose;Wake-up time; | — |
Countries
China
Contacts
Public ContactYang Xiaomei
Qilu Hospital
Outcome results
None listed