prolactinoma
Conditions
Interventions
Group A:Germinated barley (Maiya) plus bromocriptine
Group B:Bromocriptine
Sponsors
Huashan Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Clinical diagnosis of prolactinoma with typical clinical manifestations and continuous elevation of serum prolactin level; 2.The prolactin level did not decrease to normal after at least 3 months of bromocriptine treatment with stable dose; 3.Age: 18 - 70 years; No gender limitation; 4.Voluntarily participate and sign informed consent.
Exclusion criteria
Exclusion criteria: 1.Other causes of hyperprolactinemia such as drug induced, physiological, hypothyroidism, stalk effect,etc.; 2.Cabergoline treatment; 3.History of serious heart, liver, kidney, brain, hematopoietic system diseases or mental diseases; 4.Pregnant women or women who have planned to be pregnant in the following six months; 5.Surgical indications (individuals who refuse to take long-term medication, acute apoplexy of pituitary tumor, progressive decline of vision, cerebrospinal rhinorrhea after medication, etc.); 6.Those who have received pituitary surgery or radiotherapy within six months. 7.Allergic to Maiya.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage reduction in prolactin levels;Remission rate of clinical symptoms;Proportion of side effects of bromocriptine; | — |
Secondary
| Measure | Time frame |
|---|---|
| Normal proportion of prolactin levels;Change of pituitary adenoma size; | — |
Countries
China
Contacts
Public ContactBin Lu
Huashan Hospital Affiliated to Fudan University
Outcome results
None listed