Establish multidisciplinary management project for secondary hyperparathyroidism in kidney transplantation recipients

The effect of posttransplant vitamin D supplementation on kidney transplantation recipients with secondary hyperparathyroidism

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200056077

Enrollment

Unknown

Registered

2022-01-31

Start date

2022-01-31

Completion date

Unknown

Last updated

2024-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Secondary hyperparathyroidism

Interventions

Group 1 :cholecalciferol

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Aged between 18-65 years; 2.Received first kidney transplantation and being followed regularly at West China Hospital.

Exclusion criteria

Exclusion criteria: 1.Acute rejection and infection occurred within 4 weeks prior to the vitamin D supplementation; 2.Delayed graft function (DGF); 3.Parathyroidectomy before transplantation; 4.ABO-incompatible transplantation; 5.History of malignancy, 6. Auto-immune diseases and primary parathyroid disease.

Design outcomes

Primary

Measure	Time frame
parathyroid hormone;25 hydroxyvitamin D;Fibroblast growth factor 23;aKlotho;Serum creatinine;	—

Secondary

Measure	Time frame
Serum calcium;Serum phosphate;Bone specific alkaline phosphatase;Bone density;CD4+ Regulatory T cells;helper T cell 17;T follicular helper cells;chemokine (CXC motif) 10;chemokine receptor (CXC motif) 3;high mobility group box-1 protein;coronary calcification score;interleukin 2;interleukin 6;interleukin 10;interferon-?;interleukin 17A;tumor necrosis factor a;	—

Countries

China

Contacts

Public ContactShi Yunying

West China Hospital, Sichuan University

yyshi0130@163.com+86 18980605862

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026