Cesarean section
Conditions
Interventions
Group R:Intrathecal (I/T) ropivacaine 12mg
Group RD1:I/T ropivacaine 12 mg +dexmedetomidine 5 µg
Group RD2:I/T ropivacaine 12 mg +dexmedetomidine 7.5 µg
Group RD3:I/T ropivacaine 12 mg +dexmedetomidine 10 µg
Sponsors
The First Affiliated Hospital of Gannan Medical College, Ganzhou, Jiangxi
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Singleton pregnancy; 2. American Society of Anesthesiologists (ASA) physical status I-II; 3. Aged between 20 and 45 years; 4. Gestational age >= 37 weeks.
Exclusion criteria
Exclusion criteria: 1. Had contraindications to regional anesthesia; 2. Hypertension; 3. Cardiopulmonary disease; 4. Chronic users of adrenergic receptor blockers or calcium channel blockers; 5. A known history of alcohol or substance abuse; 6. Pregnancy comorbidities; 7. Allergies to any of the drugs used in the study; 8. A history of psychiatric disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anesthesia effect;Intraoperative adverse reactions;Mean arterial pressure;Heart rate;SpO2;Cortisol;Adrenaline;Norepinephrine;Prolactin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Onset time and duration of sensory block;Onset time and duration of motor block;Fluid dynamics fluctuation and vasoactive drug use;Postoperative adverse reactions;Apgar score; | — |
Countries
China
Contacts
Public ContactZhong Maolin
The First Affiliated Hospital of Gannan Medical College
Outcome results
None listed