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A single blind randomized controlled study on the analgesic effect of femoral nerve block combined with low concentration ropivacaine anterior sciatic nerve block or intra-articular local anesthetic injection after unilateral total knee arthroplasty

A single blind randomized controlled study on the analgesic effect of femoral nerve block combined with low concentration ropivacaine anterior sciatic nerve block or intra-articular local anesthetic injection after unilateral total knee arthroplasty

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200056048
Enrollment
Unknown
Registered
2022-01-31
Start date
2022-02-01
Completion date
Unknown
Last updated
2024-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total knee arthroplasty

Interventions

experimental group:Sciatic nerve block and femoral nerve block
control group:Local infiltration of articular cavity and femoral nerve block

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients to undergo single knee arthroplasty; 2. Aged 60 to 80 years, weight 50-90kg, ASA grade I-II; 3. No contraindications of intraspinal anesthesia; 4. Normal cognitive function; 5. Informed consent was signed during the pre-anesthesia visit.

Exclusion criteria

Exclusion criteria: 1. Contraindications of the nerve blockade (abnormal coagulation function, infection at the puncture site, etc.); 2. Unable to cooperate to complete nerve block (patients with unconsciousness or mental abnormalities); 3. Hypersensitivity to ultrasound coupler, local anesthetics, or opioids; 4. Long-term oral analgesics.

Design outcomes

Secondary

MeasureTime frame
Lower limb muscle strength;Knee and Ankle Mobility;Adverse reactions;

Primary

MeasureTime frame
Visual analog score;

Countries

China

Contacts

Public ContactLiwei Wang

Peking University Third Hospital

408670153@sina.com+86 15201304191

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026