stroke
Conditions
Interventions
Experimental group:short-term exercise
Control group :No exercise intervention
Sponsors
Huashan Hospital Fudan University
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of "China Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018", including: (1) Acute onset; (2) Focal neurological deficit or comprehensive neurological deficit; (3) Imaging with responsible lesions or symptoms/signs lasting more than 24 hours; (4) Exclude non-vascular causes; (5) Brain CT/MRI to exclude cerebral hemorrhage. 2. Subacute stage of disease course (7 days to 6 months). 3. Aged 40-75 years, gender is not limited. 4. Vital signs are stable, able to complete routine post-stroke rehabilitation assessment and treatment. 5. Unilateral hemiplegia, lower limb Brunnstrom stage >= stage III, able to complete the CPET test and perform power cycling training. 6. Informed consent and voluntary participation in the researcher.
Exclusion criteria
Exclusion criteria: 1. Severe or uncontrollable high blood pressure, severe cardiac insufficiency, severe infection (pneumonia, etc.), diabetic ketosis, frequent epilepsy, and other diseases that clinicians believe may worsen by exercise; 2. There are uncontrolled clinical conditions (hyperthyroidism or hypothyroidism, severe liver and kidney damage, the acute activity of rheumatic diseases, electrolyte imbalance, severe anemia, etc.); 3. The patient has participated in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VO2peak;HRpeak;BPpeak; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fugl-Meyer;Serum immunological indexes;MESSS;NIHSS;Berg balance scale;BDNF;SmO2;Cerebral blood flow;TMS-MEP;fMRI;DTI;MRS; | — |
Countries
China
Contacts
Public ContactJie Jia
Huashan Hospital Fudan University
Outcome results
None listed