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Clinical observation of pulse radiofrequency of thoracic dorsal root ganglion combined with local subcutaneous ozone in the treatment of postherpetic neuralgia

Clinical observation of pulse radiofrequency of thoracic dorsal root ganglion combined with local subcutaneous ozone in the treatment of postherpetic neuralgia

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200056039
Enrollment
Unknown
Registered
2022-01-31
Start date
2022-02-01
Completion date
Unknown
Last updated
2024-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

herpes zoster

Interventions

congtrol group 1:Pregabalin capsules (75 mg) BID, mecobalamin (0.5mg) TID
control group 2:Pregabalin capsule (75 mg) BID, mecobalamin (0.5mg) TID, pulse radiofrequency of thoracic dorsal root ganglion
observation group:Pregabalin capsules (75 mg) BID, mecobalamin (0.5mg) TID, thoracic dorsal root ganglion pulse radiofrequency combined with local subcutaneous ozone injection

Sponsors

The Third People's Hospital of Hangzhou
Lead Sponsor

Eligibility

Sex/Gender
All
Age
55 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Meet the relevant diagnostic criteria for postherpetic neuralgia; 2. Onset time 1-3 months; 3. Aged > 55 years; 4. The lesions involved thoracic dorsal root ganglion; 5. VAS (Visual Analogue Scale) score > 3, sleep was affected by pain.

Exclusion criteria

Exclusion criteria: 1. There are many complicated diseases, such as serious heart and lung diseases, liver and kidney damage and coagulation dysfunction; 2. Patients with mental disorders and other diseases that cannot cooperate with the treatment operation; 3. Patients who have received pulse radiofrequency, radiofrequency thermocoagulation, nerve block or other minimally invasive interventional therapy; 4. Ozone allergy; 5. Peripheral local skin infection.

Design outcomes

Primary

MeasureTime frame
Visual Analogue Scale;Pittsburgh sleep quality index, PSQI;Short From Health Survey,SF-36;

Secondary

MeasureTime frame
Self-Rating Anxiety Scale, SAS;

Countries

China

Contacts

Public ContactYang Lu

The Third People's Hospital of Hangzhou

luyang515898876@163.com+86 13621886441

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026